ABSTRACT
The world is recovering from Covid-19, and along with that it has brought the zeal to use the digital media, concepts like work from home, connecting the whole world using applications and social media. However, with good things follow bad and we observe a lot of people being affected by social engineering attack via multiple means be it as elementary as an unfamiliar person calling us to ask us about our day or complicated and puzzling as someone acting like the victim's senior. In some cases, people are aware of the process but are unaware of the terms they are victimized with others do not know many kinds of social engineering attacks. Therefore, it is imperative for an organization and an individual that they are aware of how Social Engineering is carried out. In this paper, we represent the survey filled by more than 100 people from diverse age groups and work profiles seeking their views on the attack and knowledge about social engineering. © 2022 IEEE.
ABSTRACT
The clinical outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection include asymptomatic disease or mild disease with influenza-like symptoms or severe disease condition following death by pneumonia and acute respiratory distress syndrome (ARDS). The current mRNA- and vector-based vaccines successfully addressed the antigenic challenges of the parental SARS-CoV-2 strain. However, recent concerns are being raised against some SARS-CoV-2 variants, which have the potential to escape natural immunity and vaccine-induced immune recognition partially, leading to a possible increase in transmissibility and disease severity. The coronavirus disease-19 (COVID-19)-induced rapid changes in human immune profiles might be instigating the evolution of SARS-CoV-2 with a higher propensity. Therefore, we require critical surveillance on the genomic sequence and structural conformation of the evolving variants and phenotypic impacts of the accumulating mutations on the host-immune response for possible updates in the booster vaccine sequence, if required. Here, we will highlight the role of accumulating mutations in SARS-CoV-2 genomic sequences leading to the host-immune escape by regulating the T cell- and B cell-mediated responses in infected, unvaccinated, and vaccinated individuals. © 2023 Elsevier Inc. All rights reserved.
ABSTRACT
In the new paradigm of health-centric governance, policymakers are in constant need of appropriate metrics to determine suitable policies in a non-arbitrary fashion. To this end, in this paper, a compartmentalized model for the transmission of COVID-19 is developed, with a socially distanced compartment added to the model. The modification allows for administrators to quantify the extent to which voluntary social distancing norms are followed, and address restrictions accordingly. Modifications are also made to incorporate inter-region migration, and suitable metrics are proposed to quantify the impact of migration on the rise of cases. The healthcare capacity is modeled and a method is developed to study the consequences of the saturation of the healthcare system. The model and related measures are used to study the nature of the transmission and spread of COVID-19 in India, and appropriate insights are drawn. Copyright © 2022 World Scientific Publishing Company.
ABSTRACT
In order to analyze the progression of COVID-19 outbreak in India, we present a data-driven analysis, by the consideration of four different metrics, namely, reproduction rate, growth rate, doubling time and death-to-recovery ratio. The incidence data of the COVID-19 (during the period of 2nd March 2020 to 11th September 2021) outbreak in India was analyzed, based on the estimation of time-dependent reproduction. The analysis suggested effectiveness of the lockdown, in arresting the growth and this continued for the post-lockdown period, except for the period of the setbacks resulting for the second wave. The approach adopted here would be useful in future monitoring of pandemics, including its progression. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
ABSTRACT
The demand and consumption of hand sanitizers have increased throughout the world with the beginning of the pandemic of COVID-19. It had led to a reduction in these products at all levels. Big companies, firms, and malls have installed automatic touchless hand sanitizer machines. These are used to prevent the spread of the virus among the masses. But in our homes, we tend to use the same pump hand sanitizer bottle after coming from outside. This increases the chance of spreading the virus among our dear ones. So, we thought of making an Automated (Do-it-yourself) hand sanitizer for our homes. © 2022 IEEE.
ABSTRACT
In the current scenario the world is suffering due the SARS-Cov-2 or corona virus. It was first originated in Wuhan, China in 31st December 2019 and spread all over the world with a very short time. It killed more than eight lakh ninety six thousand people in all over the world where as affected two crore seventy five lakh people within this period. Till now there is no potential approved vaccine or medicine is not available in the world. However, some drugs are indicating a potential against the deadly virus. This review is aiming to identify those drugs which are potential against the SARS- CoV2. As per research papers and several reports there are 4 classes of drugs which will be effective against the Corona virus, they are i) Anti-viral drugs and anti-inflammatory drugs ii) Anti H.I.V drugs iii) Anti-malarial drugs iv) Traditional Chinese dugs and other types of drugs. Though these drugs may be partially effective against the Corona virus but the research should continue to find some new molecule or new vaccine to cure this disease.
ABSTRACT
The world is currently witnessing a pandemic crisis caused by SARS CoV-2 having its origin in Wuhan, China. Transformation from epidemic to pandemic within a very short time-gap resulting in massive global mortality has created a sudden global deadlock affecting both human health and wealth. Clinical symptoms expressed by affected patients include dry cough, dyspnea, fever, bilateral lung infiltration and ultimately severe acute respiratory distress in advanced stages. The disease is spread over 150 countries and termed as COVID-19 by the World Health Organization (W.H. O). As per W.H. O report on 2nd May 2020 there are over 3000000 infected cases distributed throughout the globe claiming more than 200000 lives. Mortality rate is accelerating at high speed and presently crossing 6%. The entire global healthcare system is exposed and found to be inadequate to mitigate the deadly virus. At present there is no medicine or vaccine available or clinically proven for COVID-19 management. However, the global research spotlight is now focused on development of drugs or vaccine against the virus. This has created a long pipeline of such agents which are now under preclinical or clinical evaluation stage. Some existing drugs are also under efficacy evaluations against COVID-19 whereas some are allowed to be used as a prophylactic measure. WHO has framed clear guidelines for all countries to manage the spread of the virus and these are being implemented through existing government & regulatory bodies of specific countries. The present work will give detailed outline on the pandemic spread, transmission mode, therapeutic strategies and its impact on day to day human life.